Reduction of Aβ in Down Syndrome cells by Targeting APP splicing with ASOs

Targeting Amyloid-β Precursor Protein, APP, Splicing with Antisense Oligonucleotides Reduces Toxic Amyloid-β Production

ASO-induced LRP8/APOER2 alternative splicing

Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides.