miRNAs and Exosomes

Elevate miRNA levels with ASOs

Steric blocking ASOs increase miR-1225 by targeting processing from the primary transcript within intron 45 of PKD1

MicroRNA, exon or... both

Drosha promotes splicing of a pre-miRNA-like alternative exon



Simtrons: non-canonical miRNA processing product

Biogenesis of mammalian microRNAs by a non-canonical processing pathway

Circulating miRNAs in exosomes as biomarkers of disease

Selective release of microRNA species from normal and malignant mammary epithelial cells